Constantino Carlos Reyes-Aldasoro

Constantino Carlos Reyes-Aldasoro

Senior Lecturer in Biomedical Image Analysis at City, University of London

Estimation of apparent tumor vascular permeability from multiphoton fluorescence microscopic images of P22 rat sarcomas in vivo

Constantino Carlos Reyes-Aldasoro, Ian Wilson, Vivien E. Prise, Paul R. Barber, M. Ameer-Beg, Borivoj Vojnovic, Vincent J. Cunningham, Gillian M. Tozer

Abstract


OBJECTIVE: To develop an image processing-based method to quantify the rate of extravasation of fluorescent contrast agents from tumor microvessels, and to investigate the effect of the tumor vascular disrupting agent combretastatin A-4-P (CA-4-P) on apparent tumor vascular permeability to 40 kDa fluorescein isothiocyanate (FITC) labeled dextra”